Sirona Dx Introduces Imaging Mass Cytometry Services to Advance Biomarker Discovery and Therapeutic Development
Specialized CRO offers high-definition tissue imaging services for pharmaceutical and clinical research
Sirona Dx is a specialized contract research organization (CRO) that provides high-quality clinical research services to pharmaceutical and clinical research clients and focuses on offering early access to advanced technologies.
With a goal of providing innovative approaches to expand drug discovery pipelines and bring more effective therapies to market, Sirona Dx decided to add multiplex tissue imaging to its growing technology portfolio. Noticing impressive Imaging Mass Cytometry results from top pharmaceutical companies and leading academic medical centers, Sirona Dx engaged
“After a comprehensive evaluation of different tissue imaging technologies, Imaging Mass Cytometry was the clear choice. Imaging Mass Cytometry will enable our clients to resolve complex cellular networks and signaling pathways within tissue microenvironments with unprecedented definition,” said Nasry Yassa, Ph.D., Chief Executive Officer of Sirona Dx. “The early response from our pharma partners has been extremely positive. Our clients are expressing significant interest in using Imaging Mass Cytometry to advance their research goals and are pleased to access this new technology through an experienced CRO. Sirona Dx has exciting projects underway and additional requests coming in from top pharmaceutical companies.”
Developed for research use, Imaging Mass Cytometry enables simultaneous imaging of up to 37 protein markers from a single scan of formalin-fixed, paraffin-embedded (FFPE) or fresh tissue sections at subcellular resolution. Using proven CyTOF® technology, Imaging Mass Cytometry surpasses the inherent limitations of fluorescence detection by using high-purity metal tags that are separated by mass instead of by wavelength. With an established global footprint and 18 scientific publications to date, Imaging Mass Cytometry is rapidly setting a new standard for highly multiplexed tissue imaging.
“By preserving tissue architecture and cellular morphology information, Imaging Mass Cytometry is ideal for understanding complex tissue microenvironments. It is especially useful for monitoring changes in the immune system in a variety of disease states such as cancer or auto-immunity,” said Dr. Merchant. “With easily customizable panel designs using available pre-conjugated antibodies or metal conjugation kits, Imaging Mass Cytometry is a valuable tool for translational and clinical research across a range of disease areas.”
“Sirona Dx is our first Imaging Mass Cytometry CRO partner in the United States,” said
About Sirona Dx
Sirona Dx is a technical CRO founded to accelerate the pace of targeted therapy development to improve outcomes for cancer patients. Bridging silos between diagnostics manufacturers, translational clinical research, and clinical service labs, Sirona Dx collaborates with leading platform providers to offer pharmaceutical and clinical research clients early access to advanced technologies.
Sirona Dx operates out of a CLIA certified laboratory facility in
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