Fluidigm Introduces Advanta RNA Fusions NGS Library Prep Assay to Accelerate Translational and Clinical Cancer Research
Gene fusions are an important and growing class of genetic markers associated with human oncogenesis. These commonly occur when a DNA rearrangement creates a fusion of two different genes. Often resulting in the production of a chimeric oncogenic fusion protein or significant amplification of oncogene expression, gene fusions can drive cancer progression and influence therapeutic response.
The Advanta RNA Fusions NGS Library Prep Assay was developed to profile over 1,000 known gene fusion breakpoints present in tumor RNA, automating library preparation for subsequent analysis on Illumina® NGS platforms. Requiring as little as 10 ng of RNA material per sample, the automated microfluidic workflow reduces hands-on time and lowers reaction volumes to nanoliter scale, delivering significant cost savings per sample.
"We designed the Advanta RNA Fusions Library Prep Assay to work in concert with our new Advanta Solid Tumor Library Prep Assay for detection of both somatic variants and RNA fusions in a single, simple workflow," said David King, PhD, Vice President of Research and Development at
“Empowering the cancer community to obtain a comprehensive view of human cancers is central to our growth strategy,” said Chris Linthwaite, President and CEO of Fluidigm. "We are excited to offer these new cancer assays and enhanced workflow capabilities to fuel the identification of high-value biomarkers and accelerate therapeutic development.”
Forward-Looking Statement for
This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, including, among others, statements regarding the anticipated benefits of newly introduced products and the growth and potential of cancer research. Forward-looking statements are subject to numerous risks and uncertainties that could cause actual results to differ materially from currently anticipated results, including but not limited to risks relating to challenges inherent in developing, manufacturing, launching, marketing, and selling new products; potential product performance and quality issues; intellectual property risks; and competition. Information on these and additional risks and uncertainties and other information affecting Fluidigm business and operating results is contained in Fluidigm’s Annual Report on Form 10-K for the year ended December 31, 2018, and in its other filings with the Securities and Exchange Commission. These forward-looking statements speak only as of the date hereof. Fluidigm disclaims any obligation to update these forward-looking statements except as may be required by law.
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Source: Fluidigm Corporation